Prurigo nodularis - Nodularis Prurigo
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ReferencesIs riocht craiceann fada buan é Prurigo nodularis; tá sainairíonna ann sna bumps agus nodules gnólachta iolracha, a fhaightear de ghnáth ar chodanna seachtracha na n-arm agus na gcosa. D’fhéadfadh dath éagsúil a bheith ar na cnapáin seo, ó dhath feola go bándearg, agus bíonn siad an-priontáilte. Is féidir leo dul i bhfeidhm ar dhaoine d’aois ar bith, agus is minic a bhíonn siad nasctha le coinníollacha craicinn eile a chuireann le tochas ainsealach de bharr dermíte atópach. I measc na roghanna cóireála tá cógais láidre frith‑priontáil, drugaí a théann i bhfeidhm ar an gcóras imdhíonachta, agus cógais a dhíríonn ar an néarchóras. Is gnách go mbíonn teiripe fadtéarmach i gceist le bainistiú Prurigo nodularis.
Prurigo nodularis is a chronic disorder of the skin that is classically seen as multiple, firm, flesh to pink colored papules, plaques and nodules commonly located on the extensor surfaces of the extremities. The lesions are very pruritic and can occur in any age group. It is commonly associated with another disease such as atopic dermatitis or any dermatoses associated with chronic pruritus. The therapeutic approach is wide-arrayed ranging from treatments that act as - potent antipruritics, immunomodulators, and neuromodulators. Treatment in an established case is prolonged and improving patient compliance with education and counseling is important.
Prurigo nodularis is a chronic disorder of the skin that is classically seen as multiple, firm, flesh to pink colored papules, plaques and nodules commonly located on the extensor surfaces of the extremities. The lesions are very pruritic and can occur in any age group. It is commonly associated with another disease such as atopic dermatitis or any dermatoses associated with chronic pruritus. The therapeutic approach is wide-arrayed ranging from treatments that act as - potent antipruritics, immunomodulators, and neuromodulators. Treatment in an established case is prolonged and improving patient compliance with education and counseling is important.
De ghnáth, is éard atá i gceist le cóireáil ná úsáid a bhaint as uachtair nó instealltaí stéaróidigh ar an limistéar difear. I gcásanna níos tromchúisí, d’fhéadfadh gá le cóireálacha cosúil le teiripe éadrom nó cógais a shochtann an córas imdhíonachta. Is roghanna iad thalidomide agus lenalidomide do chásanna tromchúisí, ach is féidir le fo‑iarsmaí tromchúisí a bheith acu. Léiríonn cóireálacha níos nuaí (opioid receptor antagonists, neurokinin-1 receptor antagonists) gealltanas maidir le prurigo nodularis a chóireáil le níos lú fo‑iarsmaí i gcomparáid le thalidomide nó lenalidomide.
Treatment typically relies on the use of topical or intralesional steroids, though more severe or recalcitrant cases often necessitate the use of phototherapy or systemic immunosuppressives. Thalidomide and lenalidomide can both be used in severe cases; however, their toxicity profile makes them less favorable. Opioid receptor antagonists and neurokinin-1 receptor antagonists represent two novel families of therapeutic agents which may effectively treat PN with a lower toxicity profile than thalidomide or lenalidomide.
Treatment typically relies on the use of topical or intralesional steroids, though more severe or recalcitrant cases often necessitate the use of phototherapy or systemic immunosuppressives. Thalidomide and lenalidomide can both be used in severe cases; however, their toxicity profile makes them less favorable. Opioid receptor antagonists and neurokinin-1 receptor antagonists represent two novel families of therapeutic agents which may effectively treat PN with a lower toxicity profile than thalidomide or lenalidomide.
Is riocht craicinn é Chronic prurigo a bhaineann le tochas fadtéarmach (marthanach níos mó ná 6 seachtaine), le craicinn a bhaineann le scratch, agus stair de scriobhadh go minic. Baineann sé le neuroinflammation agus fiobróis sa chraiceann.
Chronic prurigo (CPG) is a neuroinflammatory, fibrotic dermatosis that is defined by the presence of chronic pruritus (itch lasting longer than 6 weeks), scratch-associated pruriginous skin lesions and history of repeated scratching.
Chronic prurigo (CPG) is a neuroinflammatory, fibrotic dermatosis that is defined by the presence of chronic pruritus (itch lasting longer than 6 weeks), scratch-associated pruriginous skin lesions and history of repeated scratching.
Prurigo nodularis is fadhb chraiceann a mhaireann le fada, atá marcáilte le nodúlacha crúite. Níl a fhios againn go díreach cad a chuireann ar bun an choróin, ach tá sé cosúil le go bhfuil ról ag saincheisteanna imdhíonachta agus neart sa timthriall prúda‑greann. Faoi láthair, níl aon chóireálacha ceadaithe ag an US FDA go sonrach le haghaidh Prurigo nodularis.
Prurigo nodularis is a long-lasting skin problem marked by itchy nodules. We don't know exactly what causes it, but it seems that immune and nerve issues play a role in the itch-scratch cycle. Right now, there aren't any treatments approved by the US FDA specifically for prurigo nodularis.
Prurigo nodularis is a long-lasting skin problem marked by itchy nodules. We don't know exactly what causes it, but it seems that immune and nerve issues play a role in the itch-scratch cycle. Right now, there aren't any treatments approved by the US FDA specifically for prurigo nodularis.
○ Cóireáil – Drugaí OTC
Ní chuireann sé ar bith le laghdú an loite agus d’fhéadfadh sé an scátha a dhéanamh níos measa. Féadfaidh ointments steroid thar an gcúinne cabhrú le na hairíonna a mhaolú, ach de ghnáth caithfidh tú iad a chur i bhfeidhm ar feadh roinnt seachtainí chun feabhas a fheiceáil. Cabhraíonn leantú ar fhreagrachtaí frithhistamín a ghlacadh chun an tochas a mhaolú.
#OTC steroid ointment
#OTC antihistamine
○ Cóireáil
#Intralesional triamcinolone injection